N2-Dimethylguanosine
CAS No.:2140-67-2
Modified nucleoside synthon.
N2-Dimethylguanosine
2'-Deoxy-4-desmethylwyosine
CAS No.:101803-00-3
A convenient synthon for the preparation on N-2-alkyl derivatives of 2'-deoxyguanosine.
5-Methyl-2'-deoxycytidine Hydrochloride
CAS No.:838-07-3 (Free Base) 5241-10-1 (HCl Salt)
Modified nucleoside synthon.
2-Methyladenosine
CAS No.:16526-56-0
Modified nucleoside synthon.
N6-Benzoyl-5'-O-(dimethoxytrityl)-8-oxo-2'-deoxyadenosine
CAS No.:142979-41-7
Modified nucleoside synthon.
α-2'-Deoxyguanosine
CAS No.:19916-78-0
Modified nucleoside synthon.
5-Ethynyl-2'-deoxyuridine
CAS No.:61135-33-9
Modified nucleoside synthon.
1,3-Dimethylpseudouridine
CAS No.:64272-68-0
Modified nucleoside synthon.
8-Azanebularine
CAS No.:38874.46-3
Modified nucleoside synthon.
5-Formylcytidine
CAS No.:148608-53-1
Modified nucleoside synthon.
N6-Methyl-2'-deoxyadenosine
CAS No.:2002-35-9
Useful methylated adenosine synthon.
2-Amino-2'-deoxyadenosine
CAS No.:4546-70-7
Nucleoside synthon useful in duplex stabilisation.
3'-Deoxythymidine
CAS No.:05.05.3416 00:00:00
Modified nucleoside synthon.
N4-[(Dimethylamino)methylidene]-5-[3-oxo-[[6-[(trifluroacetyl)amino]-hexyl]amino]-1-propenyl]-2'-deoxycytidine
Modified nucleoside synthon.
Cytidin-5-yl-methanesulfonate sodium salt hydrate
Modified nucleoside synthon.
3',5'-Di-O-acetyl-2'-deoxyguanosine
CAS No.:69992-10-5
Modified nucleoside synthon.
3-Methylcytidine
Modified nucleoside synthon.
Formycin A
CAS No.:07.12.6742 00:00:00
A potent purine nucleoside antibiotic with a C-glycosidic linkage between the ribosyl moiety and the pyrazolopyrimidine base.
5-Methoxyuridine
CAS No.:35542-01-9
Modified nucleoside synthon.
2'-O-Methyluridine
CAS No.:2140-76-3
Modified nucleoside synthon.
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Modified Nucleosides
Modified nucleosides are useful building blocks for DNA and RNA synthesis because they can alter the stability, function, and utility of an oligo, making them useful for a variety of applications.
Our uniquely large collection of modified nucleosides offers a diversity of properties such as fluorescence (e.g., Pyrrolo-dC, NACR1-350), immunostimulation (e.g., 5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione, NACR1-366), enzyme inhibition (e.g., Tricyclic Nucleoside Monophosphate, NACR1-362), and altered base-pairing (2'-Deoxyisoguanosine, NACR1-071).
Highlights of modified nucleosides within our collection include:
- Bromo- and Iodo-modified nucleoside phosphoramidite precursors (Bromo: NACR1-001, NACR1-003; Iodo: NACR1-002, NACR1-004)
- 5-Hydroxymethyl-2'-deoxycytidine (NACN4-007), 5-Formyl-2’-deoxycytidine (NACN4-003), and 5-Hydroxy-2'-deoxycytidine (NACN4-004) for epigenetic studies
- Family of Pseudouridine analogues including Pseudouridine (Fermentation NACR1-348; Synthetic NACR1-368) and N1-Methypseudouridine (NACR1-311)
- Unnatural bases (dNaM, NACR1-304; d5SICS, NACR1-302) for expanding the genetic alphabet and “DNA damaged” nucleosides (e.g., 8-Oxo-2'-deoxyguanosine, NACR1-292; 8-Oxo-2'-deoxyadenosine, NACR1-291)