Blood samples can present a myriad of challenges due to their inherent variability in quality. These variations can have a significant impact on downstream analyses, leading to inconsistent results and affecting the reliability of molecular testing protocols.

The sbeadex Blood DNA Purification Kit addresses these challenges by offering a robust and standardized method to overcome the inherent complexities of blood samples. The kit enables researchers to consistently obtain high-quality DNA from various blood sample types, including whole blood, buffy coats, and samples collected with different anticoagulants like EDTA, heparin, and citrate.

The kit's ease of automation and high-throughput capabilities allow it to seamlessly scale up sample processing using popular robotic platforms like the ThermoFisher™ KingFisher™ magnetic particle processor.

Additionally, the absence of PCR inhibitors in the final eluate, achieved through a water-based wash buffer, ensures reliable downstream analyses without the risk of interference from organic solvents or chaotropic salts.

The sbeadex Technology

This kit leverages the power of sbeadex magnetic bead technology. These superparamagnetic particles, coated with sbeadex surface chemistry, employ a novel two-bind / two wash mechanism that ensures effective removal of impurities from the sample matrix. The second wash buffer in the kit is ethanol-free, eliminating any traces of ethanol that could potentially inhibit downstream reactions. Additionally, the sbeadex technology eliminates the need for a drying step before elution, further enhancing DNA quality.