Abasic CNA CPG
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Abasic CNA CPG
Abasic CNA CPG, 500 Å, 71-79 µmol/g, BULK (g)
Key features
Show- Mimics the three carbon spacing between the 3’ and 5’ hydroxyls of the sugar unit.
- Unlike C3, modifier sits directly in the natural sugar-phosphate backbone with no adverse effect.
- Standard bulk density 0.25-0.33 g/cc.
Usually shipped in 4+ Weeks, Made To Order
Product information
A spacer C3 moiety, when incorporated into an oligonucleotide, mimics the three carbon spacing between the 3’ and 5’ hydroxyls of the sugar unit. Although useful where the base at a specific site is unknown, the flexibility of the alkyl chain distorts the sugar-phosphate backbone. This can be alleviated an abasic spacer since incorporation of this modifier sits directly into the natural sugar-phosphate backbone with no adverse effect. This modifier mimics abasic sites and is useful in the study of mutations resulting from depurination.
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