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UltraMILD phenoxyacetyl (Pac) monomers are designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.

Phenoxyacetyl (Pac) protected 2'-OTBDMS phosphoramidite for the incorporation of ribo-A into a synthetic oligonucleotide using UltraMILD conditions.

Phosphoramidite used to incorporate a deoxyadenosine into an oligonucleotide, with a methylated backbone.

UltraMILD phenoxyacetyl (Pac) monomers are designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.

CPG column for the incorporation of unmodified ribo-A at the 3' end of an oligonucleotide.

CPG column for incorporation of unmodified ribo-G at 3' end of an oligonucleotide.

Phenoxyacetyl (Pac) protected 2'-OTBDMS phosphoramidite for incorporation of ribo-G into a synthetic oligonucleotide using UltraMILD conditions.

CPG column for incorporation of unmodified dG at 3' end of an oligonucleotide.

CPG column for incorporation of unmodified ribo-G at 3' end of an oligonucleotide.

Phenoxyacetyl (Pac) protected phosphoramidite for the incorporation of a 2'-O-methyl modified ribo-A nucleobase within an oligonucleotide using UltraMILD conditions