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8-oxo-dG(iBu) CE-Phosphoramidite

8-oxo-dG(iBu) CE-Phosphoramidite

CAS No.:143060-53-1

Phosphoramidite used to incorporate a 8-oxo-modified deoxyguanosine into an oligonucleotide.
  • Useful for mutagenic studies involving oxidative processes or ionisation radiation.
  • Classical isobutyryl protection.
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Product information

8-oxo-dG-CE Phosphoramidite allows investigation of the structure and activity of oligonucleotides containing an 8-oxo mutation. This is formed naturally when DNA is subjected to oxidative conditions or ionising radiation. The resulting 8-oxo modification is significant in mutagenesis and ultimately carcinogenesis.

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