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5-Hydroxymethyl-dC Cyclic Carbamate CE-Phosphoramidite

5-Hydroxymethyl-dC Cyclic Carbamate CE-Phosphoramidite

CAS No.: 1257247-42-9

Useful phosphoramidite for investigating the role of hydroxymethyl cytidine in control of gene expression.
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2'-Deocycytodine methylation is an important and well-studied modification of DNA. The cytosine methylation alters DNA structure without impacting base pairing. This modification affects binding of transcription factors and subsequent gene express and is, therefore, an important epigenetic marker.

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