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3'-Thiol Modifier oxa-C6-S-S CPG

3'-Thiol Modifier oxa-C6-S-S CPG

CPG used to incorporate a thiol functionality, with ether spacer, at the 3' end of an oligonucleotide.
  • Features ether functionality.
  • Superior oligo yield and greater maximum synthesis length than with traditional thiol modifiers.
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Product information

DNA synthesis is markedly enhanced by including ether functionality in the alkyl chain of the disulfide. Both superior oligo yield and greater maximum synthesis length are thereby achieved. To this end, we offer Thiol-modifier-oxa-6-S-S CPG (BA 0351) and phosphoramidite (BA0332) as alternative for thiol modification in oligonucleotides.

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