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3'-Thiol Modifier oxa-C6-S-S CPG Column

3'-Thiol Modifier oxa-C6-S-S CPG Column

CPG column used to incorporate a thiol functionality, with ether spacer, at the 3' end of an oligonucleotide.

Key features

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  • Features ether functionality.
  • Superior oligo yield and greater maximum synthesis length than with traditional thiol modifiers.
Option 1: Select a Pore Size
Option 2: Select a Column Type
Option 3: Select a Scale
TBD
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Product information

DNA synthesis is markedly enhanced by including ether functionality in the alkyl chain of the disulfide. Both superior oligo yield and greater maximum synthesis length are thereby achieved. To this end, we offer Thiol-modifier-oxa-6-S-S CPG (BA 0351) and phosphoramidite (BA0332) as alternative for thiol modification in oligonucleotides. 

Synthesizer
Column
Type/Description
Notes
MerMade 6,12
MerMade, syringe (all scales)
Pipette type column
A MerMade column is also known as a Supercolumn
MerMade 4, 48X, 96E, 192E, 192X
MerMade, Syringe (up to 1.3 mL)
Pipette type column
A MerMade column is also known as a Supercolumn
ABI 384 / 394
Luer
Barrel column with luer fitting at either end
Also known as ALL-FIT or Standard
Expedite 8909
Luer
Barrel column with luer fitting at either end
Also known as ALL-FIT or Standard
ABI3900
MerMade
Pipette type column
A MerMade column is also known as a Supercolumn
K&A H4, H8, H8SE, H2, H32, H64
Luer
Barrel column with luer fitting at either end
Also known as ALL-FIT or Standard
K&A S4CL/S8CL
Luer
  Barrel column with luer fitting at either end 
 Also known as Standard. For this instrument, we recommend the Luer (Standard) column as the ALL-FIT columns have a wider barrel.
Dr Oligo 48
MerMade
Pipette type column
A MerMade column is also known as a Supercolumn
 Dr Oligo 192XLc, 768XLc just plates 
 MerMade, Syringe (up to 1.3 mL) 
Pipette type column
A MerMade column is also known as a Supercolumn
 OligoMaker X12, 48, 192, X192, X96 
MerMade, Syringe (up to 1.3 mL)
Pipette type column
A MerMade column is also known as a Supercolumn

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