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5'-Amino-dT CE-Phosphoramidite

5'-Amino-dT CE-Phosphoramidite

CAS No.:194034-71-4

Phosphoramidite to incorporate an amino-dT at the 5' end of an oligonucleotide.

Key features

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  • Incorporates primary amine-modified dT to 5' end of an oligonucleotide, for subsequent conjugation.
  • Acid-labile monomethoxytrityl (MMT) protection, used as ‘handle’ in e.g. cartridge purification where the MMT group is removed during the purification process.
  • MMT group can also be removed by extended deblocking on the synthesizer, allowing a solid-phase conjugation of a label containing e.g. an activated carboxylic acid.
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