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Desthiobiotin N-Hydroxysuccinimide Ester

Desthiobiotin N-Hydroxysuccinimide Ester

Desthiobiotin N-Hydroxysuccinimidyl Ester, 500 mg, Glass Screw-Top

CAS No.:80750-24-9

For affinity capture via the biotin-streotavidin interaction.
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Item ID BT1070-B500
TBD
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Product information

Desthiobiotin allows capture by streptavidin and can be displaced simply by adding biotin.(1) This is available as the ester (BT1070)(2), phosphoramidite (BA0210), CPG (BA0211) and azide (BT1075) versions.
Regarding association constants and kinetics, see: (a) Busse, S.; Scheumann, V.; Menges, B.; Mittler, S. Biosensors and Bioelectronics, 2002, 17, 704-710. (b) Yoon, H.C.; Hong, M.-Y.; Kim, H.-S. Langmuir, 2001, 17, 1234-1239.
For desthiobiotin itself see BT1060.

Ref:

  1. Hirsch, J.D.; Eslamizar, L.; Filanoski, B.J.; Malekzadeh, N.; Haughland, R.P.; Beechem, J. M.; Haughland, R.P. Anal. Biochem. 2002, 308, 343-357.
  2. (a) Hofmann, K.; Titus, G.; Montibeller, J.A.; Finn, F.M. Biochemistry, 1982, 21, 978-984. (b) Romovacek, H.; Finn, F.M.; Hofmann, K. Biochemistry, 1983, 22, 904-909. (c) Finn, F.M.; Titua, G.; Hofmann, K. Biochemistry, 1984, 23, 2554-2558.

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