5'-MMT-Amino Modifier 5 CE-Phosphoramidite
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5'-MMT-Amino Modifier 5 CE-Phosphoramidite
5'-MMT-Amino Modifier 5 CE-Phosphoramidite, 1 g, MerMade (30 mL / 28-400)
CAS No.:612548-86-4
Phosphoramidite for the incorporation of an amino function at the 5' end of an oligonucleotide.
Key features
Show- Incorporates primary amine to 5' end of an oligonucleotide, for subsequent conjugation.
- Acid-labile monomethoxytrityl (MMT) protection, used as ‘handle’ in e.g. cartridge purification where the MMT group is removed during the purification process.
- MMT group can also be removed by extended deblocking on the synthesizer, allowing a solid-phase conjugation of a label containing e.g. an activated carboxylic acid.
- The shorter 5-atom linker may be used to attach compounds where proximity to the oligonucleotide causes no problem.
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