Long-chain alkyl-amino CPG for base or modifier functionalisation.
Long chain alkylamine (LCAA) controlled pore glass (CPG) is used to immobilize nucleosides for synthesizing oligonucleotides.
LGC, Biosearch Technologies’ has perfected CPG manufacturing—both native and modified—for maximum oligo purity and yield. Our advanced CPG production techniques improve control of particle size and shape, pore size, pore volume and specific surface area, increasing the efficiency, purity and reproducibility of syntheses.
Biosearch Technologies offers several types of CPG, including CPG with an attached aminopropyl or long-chain alkylamine linker, ready for functionalisation, in a variety of pore sizes.
Common oligo synthesizer pack sizes are available, and for many products, you can get bulk packaging.
Several pore sizes are offered from 500 Å to 3000 Å to enable the synthesis of oligonucleotides for all applications. Which pore size required is dependent on the length, complexity and application of the oligo. Some guidelines are below for the most widely used pore sizes.
|500 Å CPG
|1000 Å CPG
|3000 Å CPG
In general, large scale oligo synthesis for therapeutic applications requires high loaded 500-600 Å and small to medium scale synthesis for diagnostic or research use require higher pores sizes.