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A number of linker variants are used in our DNA CPG products, although a long-chain alkyl amino succinyl linker is the most common. The legacy Biosearch DNA CPGs typically use the AMP-succinyl combination, but sometimes can have a glycolate linker which cleaves under mild deprotection conditions. Similarly, the Q-linker (hydroquinone-0,0'-diacetic acid group) CPGs are advantageous for quick cleavage (2 minutes at room temperature) making them ideal for base sensitive oligonucleotides or dye labelled oligos. Pore sizes commonly available are 500 Å, 1000 Å, 1400 Å and 2000 Å, with application use similar to the Prime and SynBase™ products. These CPGs utilise a different raw glass to the Prime Synthesis products, but are generally offered in smaller pack sizes for research purposes.
|Type||CPG - Bulk|