Skip to content Skip to navigation menu
cancel
  1. Home
  2. Nucleic Acid Chemistry Reagents and Instruments
  3. Nucleosides and Nucleoside Precursors
  4. Modified Nucleosides

  • 1
  • 2(current)
  • 3
  • …
  • 9

dNaM
CAS No.:1117893-19-2

Unnatural base for expansion of the genetic alphabet.

From 
VIEW
  • 1
  • 2(current)
  • 3
  • …
  • 9

Modified Nucleosides

Modified nucleosides are useful building blocks for DNA and RNA synthesis because they can alter the stability, function, and utility of an oligo, making them useful for a variety of applications.

Our uniquely large collection of modified nucleosides offers a diversity of properties such as fluorescence (e.g., Pyrrolo-dC, NACR1-350), immunostimulation (e.g., 5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione, NACR1-366), enzyme inhibition (e.g., Tricyclic Nucleoside Monophosphate, NACR1-362), and altered base-pairing (2'-Deoxyisoguanosine, NACR1-071).

Highlights of modified nucleosides within our collection include:

  • Bromo- and Iodo-modified nucleoside phosphoramidite precursors (Bromo: NACR1-001, NACR1-003; Iodo: NACR1-002, NACR1-004)
  • 5-Hydroxymethyl-2'-deoxycytidine (NACN4-007), 5-Formyl-2’-deoxycytidine (NACN4-003), and 5-Hydroxy-2'-deoxycytidine (NACN4-004) for epigenetic studies
  • Family of Pseudouridine analogues including Pseudouridine (Fermentation NACR1-348; Synthetic NACR1-368) and N1-Methypseudouridine (NACR1-311)
  • Unnatural bases (dNaM, NACR1-304; d5SICS, NACR1-302) for expanding the genetic alphabet and “DNA damaged” nucleosides (e.g., 8-Oxo-2'-deoxyguanosine, NACR1-292; 8-Oxo-2'-deoxyadenosine, NACR1-291)