3'-Deoxy-3',4'-didehydro-5-ethynylcytidine
CAS No.:1823793-27-6
Modified nucleoside synthon.
3'-Deoxy-3',4'-didehydro-5-ethynylcytidine
3-β-D-ribofuranosyl-pyrrole-2
CAS No.:16755-07-0
Modified nucleoside synthon.
2,6-Bis-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine
Modified nucleoside synthon.
Sangivamycin (4-Amino-7-(B-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine-5-carboxamide)
CAS No.:18417-89-5
Modified nucleoside synthon.
5'-Azido-2',5'-dideoxycytidine
CAS No.:4803-88-7
Modified nucleoside synthon.
1-(α)-Chloro-3,5-di-O-(p-toluoyl)-2-deoxy-D-ribose
CAS No.:4330-21-6 or 3601-89-6
Versatile carbohydrate derivative universally used for the preparation of 2'-deoxy nucleosides.
2'-Deoxyisoguanosine
CAS No.:106449-56-3
Isomeric with dG, differing by transposition of the carbonyl group at position 6 with the C-NH2 group at position 2, providing a novel hydrogen bond donor/acceptor pattern.
7-Deaza-7-octadiynylinosine
Modified nucleoside synthon.
5-(1,7-Octadiyn-l-yl)-2'-deoxyuridine
CAS No.:909398-18-1
Nucleoside useful in Click Chemistry reactions.
2',3'-Didehydro-3'-deoxythymidine (d4T)
CAS No.:3056-17-5
2',3'-Didehydro-2',3'-dideoxynucleosides (d4Ns) display antiviral activity.
Added to basket
Modified Nucleosides
Modified nucleosides are useful building blocks for DNA and RNA synthesis because they can alter the stability, function, and utility of an oligo, making them useful for a variety of applications.
Our uniquely large collection of modified nucleosides offers a diversity of properties such as fluorescence (e.g., Pyrrolo-dC, NACR1-350), immunostimulation (e.g., 5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione, NACR1-366), enzyme inhibition (e.g., Tricyclic Nucleoside Monophosphate, NACR1-362), and altered base-pairing (2'-Deoxyisoguanosine, NACR1-071).
Highlights of modified nucleosides within our collection include:
- Bromo- and Iodo-modified nucleoside phosphoramidite precursors (Bromo: NACR1-001, NACR1-003; Iodo: NACR1-002, NACR1-004)
- 5-Hydroxymethyl-2'-deoxycytidine (NACN4-007), 5-Formyl-2’-deoxycytidine (NACN4-003), and 5-Hydroxy-2'-deoxycytidine (NACN4-004) for epigenetic studies
- Family of Pseudouridine analogues including Pseudouridine (Fermentation NACR1-348; Synthetic NACR1-368) and N1-Methypseudouridine (NACR1-311)
- Unnatural bases (dNaM, NACR1-304; d5SICS, NACR1-302) for expanding the genetic alphabet and “DNA damaged” nucleosides (e.g., 8-Oxo-2'-deoxyguanosine, NACR1-292; 8-Oxo-2'-deoxyadenosine, NACR1-291)