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5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione

5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione

CAS No.:122970-40-5

An antiviral and immuno-stimulatory agent.
  • Also known as TOG, 7-thia-8-oxoguanosine, Immunosine, Immusine, Isatoribine.
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Product information

Also known as TOG, 7-thia-8-oxoguanosine, Immunosine, Immusine, Isatoribine. An antiviral and immunostimulatory agent that activates, among other things, Toll-like receptor 7 (TLR7).(1)

Ref:

  1. Lee, J.; Chuang, T.-H.; Redecke, V.; She, L.; Pitha, P. M.; Carson, D. A.; Raz, E.; Cottam, H. B., Proc. Natl Acad. Sci. USA 2003, 100, 6646-6651 and references therein.

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