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This compound has been studied for the treatment of HIV, where its ability to pair with multiple bases causes mutagenesis of the viral genome rather than exerting its effects by chain termination.(1) See also 5-aza-dC (PY7105) and 5,6-Dihydro-5-aza-dC-CE Phosphoramidite (BA0237).
- (a) Harris, K. S.; Brabant, W.; Styrchak, S.; Gall, A.; Daifuku, R., Antiviral Res. 2005, 67(1), 1-9. (b) Murakami, E.; Basavapathruni, A.; Bradley, W. D.; Anderson, K. S., Antiviral Res. 2005, 67(1), 10-17.