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8-Aza-7-deaza-dA CE-Phosphoramidite, BULK (g), Glass Screw-Top
Isosteric with adenine but offers a different pi-electron distribution and thus an altered dipole moment.
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Oligonucleotides containing 8-aza-7-deaza-dA residues exhibit higher Tm's due to stronger base stacking interactions.(1)
- Seela, F.; Kaiser, K. Helv. Chim. Acta 1988, 71, 1813-1823.