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5'-MMT-Amino Modifier 5 CE-Phosphoramidite

5'-MMT-Amino Modifier 5 CE-Phosphoramidite

CAS No.: 612548-86-4

Phosphoramidite for the incorporation of an amino function at the 5' end of an oligonucleotide.
  • Incorporates primary amine to 5' end of an oligonucleotide, for subsequent conjugation.
  • Acid-labile monomethoxytrityl (MMT) protection, used as ‘handle’ in e.g. cartridge purification where the MMT group is removed during the purification process.
  • MMT group can also be removed by extended deblocking on the synthesizer, allowing a solid-phase conjugation of a label containing e.g. an activated carboxylic acid.
  • The shorter 5-atom linker may be used to attach compounds where proximity to the oligonucleotide causes no problem.
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