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  4. Miscellaneous Oligo Synthesis Products

Miscellaneous Oligo Synthesis Products

LGC, Biosearch Technologies offers a wide array of oligo synthesis and purification products that fit your experiment, instruments, and chemistry—from common empty synthesis columns to unique reagents.

Find what you need for your specific oligo synthesis workflow:

  • Empty columns and frits: Pack your columns for use on your synthesizer of choice
  • Oligo synthesis reagents: Modify your oligos during or after synthesis
  • Molecular traps: Protect your reagents from water and small particulates
  • Oligo purification: Prep your oligos for use and analysis

Empty columns and frits

Biosearch Technologies offers empty columns and frits, available together or separately, for several synthesizer types, including:

  • MerMade™
  • ABI 3900 and ABI 394
  • ABI Expedite

Our columns come in a variety of styles - syringe style, pipette-fitting and luer-fit.

Other oligo synthesis reagents

We offer a wide range of oligo synthesis products so you can create, modify and probe oligos using any type of chemistry.

Product Description
2'-O-MOE dT CNA CPG Low Bulk Density
NACP4-002		 CPG for incorporation of 2'-O-methoxyethyl dT at the 3' end of an oligonucleotide
2'-O-MOE rC (Bz) CNA CPG Low Bulk Density
NACP4-003		 CPG for incorporation of 2'-O-methoxyethyl C at the 3' end of an oligonucleotide
2'-O-MOE rG (iBu) CNA CPG Low Bulk Density
NACP4-004		 CPG for incorporation of 2'-O-methoxyethyl G at the 3' end of an oligonucleotide
2'-O-MOE rU CNA CPG Low Bulk Density
NACP4-005		 CPG for incorporation of 2'-O-methoxyethyl U at the 3' end of an oligonucleotide
2'-O-MOE-rA (Bz) CNA CPG Low Bulk Density
NACP4-006		 CPG for incorporation of 2'-O-methoxyethyl A at the 3' end of an oligonucleotide
3'-Fluorous Modifier CPG
NACP7-027		 Place a permanent fluorous tag at the 3'-terminus of an oligonucleotide for immobilization, enabling intra- and intermolecular interactions, or purification  
4'-Chloromethyl-4,5',8-trimethylpsoralen
NACP4-018		 Attach various linkers to the psoralen ring system
4'-Hydroxymethyl-4,5',8-trimethylpsoralen (HMT)
NACP4-020		 Intercalate into and photoalkylate dsDNA for targeted mutagenesis and photochemotherapy
6-Chlorosalicylic Acid
NACP4-022		 A biodegredation product of the herbicide Dicamba
AmAz Coupler
NACP4-023		 Link an amine-containing component to an azide-containing component 
Glutathione Reductase Probe
NACP4-028		 Quickly detect thiol detection with a coumarin-based fluorophore and maleimide as the thiol acceptor
Luminol Synthon N-hydroxysuccinimide Ester
NACP4-030		 Post-synthetically modify oligonucleotides for chemiluminescence studies
MMBC (Methyl Maleimidobenzochromenecarboxylate; ThioGlo® 1)
NACP4-031		 Detect thiol-containing proteins, enzymes and peptides  
TInsP5
NACP4-036		 A novel chromophoric substrate analog of phytic acid used to measure phytase activity.

Molecular Traps

Molecular Traps™ are highly activated molecular sieve packets designed to provide and maintain very low water levels in water-sensitive solvents and solutions.

We provide Molecular Traps that will maintain sub-50 ppm water levels in the acetonitrile and activator bottles directly on the instrument without issues of clogging valves or restrictors with sieve dust or pouch ‘fuzz’.

  • Removes water and small particles from reagent solutions
  • Conveniently packaged in different sizes
  • Tested on selected DNA synthesizers

Oligo purification

Fluorous affinity purification

Fluorous affinity purification is a fast and simple method for purifying oligonucleotides. The method relies on the strong interaction of fluorous-tagged oligonucleotides with the fluorinated adsorbent present in Fluoro-Pak™ columns.

At Biosearch Technologies, you can find phosphoramidites, purification modifiers, loading buffers and Fluoro-Pak columns to enable your fluorous affinity purification workflow.

Learn more about fluorous affinity purification from Berry & Associates.

Purifying trityl-protected oligonucleotides

Select one of our columns below for reverse-phase purification of trityl-protected oligonucleotides followed by on-column detritylation. The method is rapid, efficient and several samples can be purified simultaneously.