Enables FDMT-on fluorous affinity purification without having to purchase individual FDMT-bearing nucleoside phosphoramidites.
For the chemical phosphorylation of oligonucleotides with concomitant fluorous affinity purification.
Miscellaneous Oligo Synthesis Products
LGC, Biosearch Technologies offers a wide array of oligo synthesis and purification products that fit your experiment, instruments, and chemistry—from common empty synthesis columns to unique reagents.
Find what you need for your specific oligo synthesis workflow:
- Empty columns and frits: Pack your columns for use on your synthesizer of choice
- Oligo synthesis reagents: Modify your oligos during or after synthesis
- Molecular traps: Protect your reagents from water and small particulates
- Oligo purification: Prep your oligos for use and analysis
Empty columns and frits
Biosearch Technologies offers empty columns and frits, available together or separately, for several synthesizer types, including:
- ABI 3900 and ABI 394
- ABI Expedite
Our columns come in a variety of styles - syringe style, pipette-fitting and luer-fit.
Other oligo synthesis reagents
We offer a wide range of oligo synthesis products so you can create, modify and probe oligos using any type of chemistry.
|2'-O-MOE dT CNA CPG Low Bulk Density
|CPG for incorporation of 2'-O-methoxyethyl dT at the 3' end of an oligonucleotide|
|2'-O-MOE rC (Bz) CNA CPG Low Bulk Density
|CPG for incorporation of 2'-O-methoxyethyl C at the 3' end of an oligonucleotide|
|2'-O-MOE rG (iBu) CNA CPG Low Bulk Density
|CPG for incorporation of 2'-O-methoxyethyl G at the 3' end of an oligonucleotide|
|2'-O-MOE rU CNA CPG Low Bulk Density
|CPG for incorporation of 2'-O-methoxyethyl U at the 3' end of an oligonucleotide|
|2'-O-MOE-rA (Bz) CNA CPG Low Bulk Density
|CPG for incorporation of 2'-O-methoxyethyl A at the 3' end of an oligonucleotide|
|3'-Fluorous Modifier CPG
|Place a permanent fluorous tag at the 3'-terminus of an oligonucleotide for immobilization, enabling intra- and intermolecular interactions, or purification|
|Attach various linkers to the psoralen ring system|
|Intercalate into and photoalkylate dsDNA for targeted mutagenesis and photochemotherapy|
|A biodegredation product of the herbicide Dicamba|
|Link an amine-containing component to an azide-containing component|
|Glutathione Reductase Probe
|Quickly detect thiol detection with a coumarin-based fluorophore and maleimide as the thiol acceptor|
|Luminol Synthon N-hydroxysuccinimide Ester
|Post-synthetically modify oligonucleotides for chemiluminescence studies|
|MMBC (Methyl Maleimidobenzochromenecarboxylate; ThioGlo® 1)
|Detect thiol-containing proteins, enzymes and peptides|
|A novel chromophoric substrate analog of phytic acid used to measure phytase activity.|
Molecular Traps™ are highly activated molecular sieve packets designed to provide and maintain very low water levels in water-sensitive solvents and solutions.
We provide Molecular Traps that will maintain sub-50 ppm water levels in the acetonitrile and activator bottles directly on the instrument without issues of clogging valves or restrictors with sieve dust or pouch ‘fuzz’.
- Removes water and small particles from reagent solutions
- Conveniently packaged in different sizes
- Tested on selected DNA synthesizers
Fluorous affinity purification
Fluorous affinity purification is a fast and simple method for purifying oligonucleotides. The method relies on the strong interaction of fluorous-tagged oligonucleotides with the fluorinated adsorbent present in Fluoro-Pak™ columns.
At Biosearch Technologies, you can find phosphoramidites, purification modifiers, loading buffers and Fluoro-Pak columns to enable your fluorous affinity purification workflow.
Learn more about fluorous affinity purification from Berry & Associates.
Purifying trityl-protected oligonucleotides
Select one of our columns below for reverse-phase purification of trityl-protected oligonucleotides followed by on-column detritylation. The method is rapid, efficient and several samples can be purified simultaneously.