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SuperPure Purification Column

SuperPure Purification Column

For reverse-phase purification of trityl-protected oligonucleotides followed by on-column detritylation (<= 50 nmol scale).
  • High performance hydrophobic polymeric resin.
  • Removes the most common impurities and truncated sequences
  • The method is rapid, efficient and many samples can be purified simultaneously.
  • Suitable for 50 nmol scale
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Product information

SuperPure Purification Columns are intended for reverse-phase purification of trityl-protected oligonucleotides followed by on-column detritylation. The method relies on strong binding between the trityl-protected product and the resin, thus allowing separation from the most common impurities, truncated sequences, which do not bind. Treatment with acid removes the DMT group from the product, the desired product (free from organic residues) is eluted with 20% acetonitrile. The method is rapid, efficient and many samples can be purified simultaneously. SuperPure is suitable for purification at the 50 nmol scale. The purified yield will depend, in each case, on sequence length and the quality of the crude sample.

Brand Biosearch
Type Accessories
Oligo Synthesis Products Oligo purification
Oligo Processing Accessories Purification

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