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LPS (Lipopolysaccharide)

LPS (Lipopolysaccharide)

LPS (Lipopolysaccharide), 10 mg, ABI (5 mL / 20 mm Septum)

Lipopolysaccharide (LPS) is the endotoxin portion of the gram-negative bacterial cell wall.
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Item ID L-1000-10
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Product information

Lipopolysaccharides (LPS) are characteristic components of the cell wall of Gram negative bacteria; they are not found in Gram positive bacteria. They are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.(1) LPS are used for research in, for example, immunology.(2) FITC (fluorescein isothiocyanate), TRITC (tetramethyrhodamine isothiocyanate), and TNP (trinitrophenyl) conjugates have been prepared by reacting LPS with either FITC, TRITC or 2,4,6-trinitrobenzenesulfonic acid, respectively.(3) They are used in research on the T-independent B cell immune response to bacterial LPS.

Ref:

  1. Analysis of Lipopolysaccharides of Gram-Negative Bacteria, H. Mayer, et al., Methods in Microbiology, 18, 157-207, 1985.
  2. Endotoxincell- membrane interactions leading to transmembrane signaling, D.C. Morrison and J.A. Rudbach, Contemporary Topics in Molecular Immunology, 8, 187-218, P. Inman and J. Mandy, eds., Plenum Press, New York, 1981.
  3. Stimulation of T-independent antibody responses by hapten-lipopolysaccharides without repeating polymeric structure, R. Skelly et al., Infect. Immun., 23, 287-293, 1979.
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